High Quality Famotidine CAS: 76824-35-6

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English name:Famotidine

CAS: 76824-35-6

Assay:≥99.0%

Appearance:White Powder

Molecular Formula:C8H15N7O2S3

Molecular Weight:337.45

Usage:Histamine H2-receptor antagonist. Antiulcerative.

Storage

Store in cool and dry area and keep away from direct sunlight.

Shelf life

2 years, keep in formal storage condition.

Reference FOB Price:$1/g

MOQ:10g

Specification:ISO9001,USP,BP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

More details pls contact:Whatapp:86 13048470428  

Skype/E-mail : summer at chembj.com

2.Description of Famotidine

Famotidine, sold under the trade name Pepcid among others is ahistamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease andgastroesophageal reflux disease.

Famotidine a histamine-2 blockers. Famotidine works by decreasing the amount of acid the stomach produces.

Unlike cimetidine, the first H2 antagonist, famotidine has no effect on the cytochrome P450 enzyme system, and does not appear to interact with other drugs.

3. Clinical Application of Famotidine

Famotidine is used to treat ulcers of the stomach and intestines and to prevent intestinal ulcers from coming back after they have healed. This medication is also used to treat certain stomach and throat (esophagus) problems (such as erosive esophagitis, gastroesophageal reflux disease-GERD, Zollinger-Ellison syndrome). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as cough that doesn't go away, stomach pain, heartburn, and difficulty swallowing.

Famotidine belongs to a class of drugs known as H2 blockers.

Famotidine also treats gastroesophageal reflux disease(GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

4.Dosage:

Usual Adult Dose for Duodenal Ulcer

Initial:

Parenteral: 20 mg IV every 12 hours. Alternatively, some clinicians recommend a continuous IV infusion of 3.2 mg/hour for up to 72 hours following a 10 mg IV bolus dose.

Oral: 40 mg orally once a day at bedtime or 20 mg orally twice a day.

Maintenance: 20 mg orally or IV once a day at bedtime.

Usual Adult Dose for Peptic Ulcer

Initial:

Parenteral: 20 mg IV every 12 hours. Alternatively, some clinicians recommend a continuous IV infusion of 3.2 mg/hour for up to 72 hours following a 10 mg IV bolus dose.

Oral: 40 mg orally once a day at bedtime or 20 mg orally twice a day.

Maintenance: 20 mg orally or IV once a day at bedtime.

Usual Adult Dose for Duodenal Ulcer Prophylaxis

20 mg orally or IV, once a day.

Usual Adult Dose for Gastric Ulcer

Parenteral: 20 mg IV every 12 hours. Alternatively, some clinicians recommend a continuous IV infusion of 3.2 mg/hour for up to 72 hours following a 10 mg IV bolus dose.

Oral: 40 mg orally once a day at bedtime or 20 mg orally twice a day.

Usual Adult Dose for Gastroesophageal Reflux Disease

Parenteral: 20 mg IV every 12 hours. Alternatively, some clinicians recommend a continuous IV infusion of 3.2 mg/hour for up to 72 hours following a 10 mg IV bolus dose.

Oral: 20 mg orally twice a day for up to 6 weeks.

Usual Adult Dose for Erosive Esophagitis

Parenteral: 20 mg IV every 12 hours. Alternatively, some clinicians recommend a continuous IV infusion of 3.2 mg/hour for up to 72 hours following a 10 mg IV bolus dose.

Oral: 20 to 40 mg orally twice a day for up to 12 weeks.

Usual Adult Dose for Zollinger-Ellison Syndrome

Parenteral: 20 mg IV every 6 hours. Alternatively, some clinicians recommend a continuous IV infusion of 3.2 mg/hour for up to 72 hours following a 10 mg IV bolus dose.