MK 677 / Ibutamoren

The effect of MK-677 :

1. Fat loss

2. Lean muscles

3. Tightening up loose skin.

4. Healing old injuries.

5. Healing Bones, Tendons and Ligaments.

6. In fact, many users report growing up to 6 lbs of lean muscle mass in 8 weeks of IGF-1 only cycles.

Doses of MK-677 :

Results have been shown from doses between 5-25mgs a day, dose dependent results should be expected. Higher doses, over 50mgs, have been reported by some, but I don’t see the need to overdo it.

Mk-677 25mg/ml solution supplier 

20ml total @ 50mg/ml

1 gram of MK-677

8.4 ml's of PEG 300

10.5 ml's 190 Proof Grain Alcohol

MK is stable in water though, so just add some alcohol to inhibit bacteria growth.

1ml of pure (95% or so) ethanol per 100ml of water is enough for sterilization.

What is MK-677 ?

Nutrobal (Mk-677) is an orally administrated growth hormone secretagogue originally developed by Reverse Pharmacology. A secretagogue is the term for a substance that chemically signals for the pituitary gland to secrete growth hormone. In other words, Nutrobal could be compared to peptides like GHRP-6 or Ipamorelin, only it doesn’t require any injections nor does it have any side effects like GHRP-6. This GHS (Growth Hormone Secretagogue) was developed in an aim to combat such conditions as muscle wasting, obesity and osteoporosis. It was also targeted towards treatment of elderly hip fracture patients, so there are a myriad of studies done on safety.Mk-2866 online supplier --Cecilia (Skype:steroid-peptide)

Growth hormone pulse intensity can be increased through 4 possible mechanisms

1. Increasing GHRH (growth hormone releasing hormone) release.

2. Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.

3. Reducing somatostatin release (somatostatin turns off GH release).

4. Inhibiting of somatostatin receptor signaling.

Nutrobal (Mk-677) was found to work through all four of these mechanisms. After ingestion, Growth Hormone (GH) was shown to increase dose dependently, at doses starting at 5 milligrams (mgs) a day.

Benefits of MK-677 :

In a study on it’s effects on catabolic states, a once daily oral dose of 25mgs was given to healthy young men subjected to short-term diet-induced nitrogen wasting. After 7 days of this dose, the subjects showed a sustained increase in serum concentration of IGF-1 and Growth Hormone; in addition, the nitrogen wasting was reversed, showing great potential for treatment of conditions involving muscle wasting. 

Trials testing the effects of this GHS on fighting obesity showed an increase in lean body mass, but neither total, nor visceral adipose tissue was effected. This study gave subjects 25mgs of Nutrobal per day for 8 weeks. The subjects showed an increase in basal metabolic rate after 2 weeks, and an increase in serum levels of GH, IGF-1 and IGF-1 binding protein-3. Increase in lean body mass was hypothesized to be caused by an increase in calorie deposition into the muscle and appetite decrease as opposed to reducing fat storage directly. 

Cycles of Mk-677 / Ibutamoren:

Mk-677

Cardarine

GW-501516

Anrdarine

(S-4)

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